the first series begins with sheriff's deputy[2] Rick Grimes waking up from a coma in an abandoned and badly damaged hospital. Leaving the hospital, Rick discovers a post-apocalyptic world overrun with zombies (or "walkers," as they are often referred to in-show). Rick also discovers his wife and son are missing. Acting on a rumor from a fellow survivor, he arms himself and begins a perilous journey to Atlanta, Georgia, where the CDC is said to have set up a quarantined safe-zone in the city. Upon reaching Atlanta, he soon discovers that the city is instead overrun by the walkers.
A few miles outside the city, Rick's wife Lori and son Carl have been hiding from the walkers with Shane Walsh, Rick's partner and best friend, who has fallen in love with Lori. They have established a camp with a small group of fellow survivors. After being rescued from Atlanta by members of the group and reunited with Lori and Carl, Rick assumes command with Shane. A band of walkers eventually attack the camp and kill several people. The remainder flee to seek aid from the CDC.
In the CDC, all but one staff member, Dr. Edwin Jenner, have either fled or killed themselves. Dr. Jenner explains that his research into the infection has not yielded a cure, and that he has not been in contact with anyone for a long while. Lack of fuel for the emergency generators soon initiates the building's safety protocols, which will trigger an explosion designed to destroy the facility and prevent the escape of deadly diseases. Jenner and Jacqui, a member of Rick's group, decide to stay and end their struggle. Dr. Jenner whispers something into Rick's ear, and the group escapes just as the CDC is incinerated in the explosion.
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